1-Methylpyrazole-4-boronic acid pinacol ester

1-Methylpyrazole-4-boronic acid pinacol ester - Names and Identifiers

Name	1-Methylpyrazole-4-boronic acid pinacol ester
Synonyms	1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2- 1-Methylpyrazole-4-boronicacidpinacol ester 1-Methylpyrazole-4-boronic acid pinacol ester 1-METHYL- 4-PYRAZOLEBORONIC ACID PINACOL ESTER 1-Methyl-4-1H-pyrazoleboronic acid, pinacol ester 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-1H-pyrazole 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole 1-Methyl-4-(4,4,5-trimethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole 1-METHYL-4-(4,4,5,5-TERAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-PYRAZOLE 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 1-Methyl-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Pyrazole 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxab orolan-2-yl)-1H-pyrazole 1-Methyl-4-pyrazoleboronic acid pinacol ester, 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
CAS	761446-44-0
EINECS	616-293-9
InChI	InChI=1/C10H17BN2O2/c1-9(2)10(3,4)15-11(14-9)8-6-12-13(5)7-8/h6-7H,1-5H3
InChIKey	UCNGGGYMLHAMJG-UHFFFAOYSA-N

1-Methylpyrazole-4-boronic acid pinacol ester - Physico-chemical Properties

Molecular Formula	C10H17BN2O2
Molar Mass	208.07
Density	1.05±0.1 g/cm3(Predicted)
Melting Point	59-64°C(lit.)
Boling Point	308.3±15.0 °C(Predicted)
Flash Point	140.272°C
Water Solubility	Slightly soluble in water.
Solubility	Chloroform (slightly), Methanol (Slightly)
Vapor Presure	0.001mmHg at 25°C
Appearance	Crystalline powder
Color	Off-white to yellow
pKa	2.09±0.10(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.505
MDL	MFCD03789259

1-Methylpyrazole-4-boronic acid pinacol ester - Risk and Safety

Risk Codes	R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection
WGK Germany	3
TSCA	No
HS Code	29349990
Hazard Note	Irritant/Flammable
Hazard Class	IRRITANT

1-Methylpyrazole-4-boronic acid pinacol ester - Reference Information

Use

1-methyl -4-(4,4,5, 5-tetramethyl-1, 3, 2-dioxopentaboran-2-yl)-1H-pyrazole is a reagent for drug synthesis, including the preparation of a selective and orally bioavailable LRRK2 inhibitor for the treatment of Parkinson's disease.
1-methylpyrazol-4-boronic acid pinacyl Ester is an agent for drug synthesis, including the preparation of a selective and orally bioavailable LRRK2 inhibitor for the treatment of Parkinson's disease.

Application

1-methyl -4-(4,4,5, 5-tetramethyl-1, 3, 2-dioxopentboran-2-yl)-1H-pyrazole is an intermediate in organic synthesis and pharmaceutical research and development, which can be used in laboratory research and development.

Last Update：2024-04-09 20:45:29